منابع مشابه
Oxygen-wasting effect of inotropy in the "virtual work model".
In the "virtual work model," left ventricular total mechanical energy (TME) is linearly related to myocardial oxygen consumption (MV˙o 2). This relationship (MV˙o 2-TME) is supposedly independent of inotropic stimulation, vascular loading, and heart rate variations. We reexamined the effect of inotropic stimulation (dopamine) on the metabolic to mechanical energy transfer in nine open-chest ane...
متن کاملOxygen wasting effect of inotropy – is there a need for a new evaluation ?
Background We addressed the hypothesis that the inotropic drugs dobutamine and levosimendan both induce surplus oxygen consumption (oxygen wasting) relative to their contractile effect in equipotent therapeutic doses, with levosimendan being energetically most efficient.
متن کاملOxygen-wasting effect of inotropy: is there a need for a new evaluation? An experimental large-animal study using dobutamine and levosimendan.
BACKGROUND We addressed the hypothesis that the inotropic drugs dobutamine and levosimendan both induce surplus oxygen consumption (oxygen wasting) relative to their contractile effect in equipotent therapeutic doses, with levosimendan being energetically more efficient. METHODS AND RESULTS Postischemically reduced left ventricular function (stunning) was created by repetitive left coronary o...
متن کاملEffect of procainamide on myocardial contractile function and digoxin inotropy.
The effect of procainamide and digoxin, singly and together, on peak active force and rate of force development of isolated right ventricular papillary muscles from adult cats was examined. Procainamide (1.5 X 10(-5) M) increased force and rate of force development in each muscle with further increments in performance up to 2.4 X 10(-4) M in most muscles. The maximal increases in force (+/- SEM...
متن کاملeffect of oral presentation on development of l2 learners grammar
this experimental study has been conducted to test the effect of oral presentation on the development of l2 learners grammar. but this oral presentation is not merely a deductive instruction of grammatical points, in this presentation two hypotheses of krashen (input and low filter hypotheses), stevicks viewpoints on grammar explanation and correction and widdowsons opinion on limited use of l1...
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ژورنال
عنوان ژورنال: Circulation: Heart Failure
سال: 2010
ISSN: 1941-3289,1941-3297
DOI: 10.1161/circheartfailure.109.865519